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Laboratory microscope
SYLVAXIS bio-based antimicrobials logoBio-based antimicrobials

Bio-based quaternary ammonium antimicrobials, DIN EN 1276 compliant including under dirty and protein-rich conditions. Active against Gram-positive and Gram-negative bacteria, including clinically relevant ESKAPE and MDR pathogens.

SYLVAXIS bio-based antimicrobial hero visual
Key facts

More potent. Safer. Bio-based.

Highly potent

At low active concentration (MIC90)

1.6 / 6.4 mg/L

MIC90 as low as 1.6 mg/L (S. aureus) and 6.4 mg/L (E. coli)

≥99 %

bacterial kill rate achieved in formulated product testing

ESKAPE / MDR

active against Gram-positive and Gram-negative bacteria, including clinically relevant ESKAPE / MDR pathogens

9 species

validated against 9 clinically relevant bacterial species, including ESKAPE pathogens

DIN EN 1276

compliant, including under dirty / protein-rich conditions

No resistance

no observed resistance build-up

Uni Graz

efficacy testing in collaboration with the Institute of Molecular Biosciences, University of Graz

TRL 4

route to market via the EU Biocidal Products Regulation (BPR)

Microscopy evidence

Action on micro-organisms.

TEM micrographs before (left) and after (right) exposure to SYLVAXIS: visible cell-wall disruption and lysis across Gram-positive (top) and Gram-negative (bottom) bacteria at low active concentrations.

Scale bars: 200 nm / 500 nm

TEM micrographs showing SYLVAXIS disrupting Gram+ and Gram− bacteria
Why it matters

Antimicrobial resistance was associated with around 4.95 million deaths globally in 2019.

SYLVAXIS offers a bio-based, high-performance alternative to fossil-based quats, with no observed resistance development.

Source: Murray et al., The Lancet, 2022 (GBD AMR Collaborators).

Target markets

Built for demanding environments.

Healthcare
Industrial & institutional (I&I) disinfection

Ready to evaluate SYLVAXIS?

Supported by

  • Supported by European Innovation Council
  • Supported by European Research Council
  • aws Austria Wirtschaftsservice
  • Research partner University of Graz
  • Research partner University of Groningen
  • Research partner TU Graz
  • Research partner Medical University of Graz
  • Supported by Creative Destruction Lab
  • Supported by chemstars.nrw
  • Supported by IECT Hermann Hauser
  • Supported by Startup-uni.at
  • Supported by BMK, Austrian Federal Ministry for Climate Action
  • Supported by Science Park Graz
Supported by European Innovation Councilaws Austria Wirtschaftsservice

Spin-off from an EIC Transition (grant agreement #101058142). Views and opinions expressed are those of the author(s) only and do not necessarily reflect those of the European Union or the European Innovation Council. The PureSurf FlexCo has received aws PreSeed funding from BMIMI.